What is the approximate frequency of Group A individuals in the U.S. population?

What is the approximate frequency of Group A individuals in the U.S. population?

• A. 41%
• B. 35%
• C. 45%
• D. 50%

Answer: (A)

Understanding ABO group frequencies in a population: Group A occurs from IAIA or IAi genotypes, so its prevalence depends on the allele frequencies of IA and i in the population. In the United States, with its mix of ethnic backgrounds, the observed distribution places Group A at roughly forty-one percent, with O around forty-five percent, B around ten percent, and AB a few percent. This makes approximately 41% the best estimate for the frequency of Group A in the U.S. population.

Understanding ABO group frequencies in a population: Group A occurs from IAIA or IAi genotypes, so its prevalence depends on the allele frequencies of IA and i in the population. In the United States, with its mix of ethnic backgrounds, the observed distribution places Group A at roughly forty-one percent, with O around forty-five percent, B around ten percent, and AB a few percent. This makes approximately 41% the best estimate for the frequency of Group A in the U.S. population.